Aspirin Research Today is a free monthly online journal that collates and summarizes the latest research about Aspirin, including details on acetylsalicylic acid, baby aspirin, side effects, overdose, allergy.

Variability and persistence of aspirin response in lower extremity peripheral arterial disease patients.

Saunders J, Nambi V, Kimball KT, Virani SS, Morrisett JD, Lumsden AB, Ballantyne CM, Dong JF,

Section of Atherosclerosis and Vascular Medicine, Department of Medicine, Baylor College of Medicine, Houston, Tex, USA. jsaunde@med.umich.edu

Published 22 February 2011 in J Vasc Surg, 53(3): 668-75.
Full-text of this article is available online (may require subscription).

Articles on Aspirin published 31 January 2011:

Associations of aspirin, nonsteroidal anti-inflammatory drug and paracetamol use with PSA-detected prostate cancer: findings from a large, population-based, case-control study (the ProtecT study).   Int J Cancer, 128(6): 1442-8.

Evidence from laboratory studies suggests that chronic inflammation plays an important role in prostate cancer aetiology. This has resulted in speculation that nonsteroidal anti-inflammatory drugs may protect against prostate cancer development. We analysed data from a cross-sectional case-control study (n(cases) = 1,016; n(controls) = 5,043), nested within a UK-wide population-based study that used prostate specific antigen (PSA) testing for identification of asymptomatic prostate cancers, to ... [Abstract] [Full-text]

Associations of aspirin, nonsteroidal anti-inflammatory drug and paracetamol use with PSA-detected prostate cancer: findings from a large, population-based, case-control study (the ProtecT study).   Int J Cancer, 128(6): 1442-8.

Evidence from laboratory studies suggests that chronic inflammation plays an important role in prostate cancer aetiology. This has resulted in speculation that nonsteroidal anti-inflammatory drugs may protect against prostate cancer development. We analysed data from a cross-sectional case-control study (n(cases) = 1,016; n(controls) = 5,043), nested within a UK-wide population-based study that used prostate specific antigen (PSA) testing for identification of asymptomatic prostate cancers, to ... [Abstract] [Full-text]

Articles on Aspirin published 24 January 2011:

Relation of aspirin failure to clinical outcome and to platelet response to aspirin in patients with acute myocardial infarction.   Am J Cardiol, 107(3): 339-42.

Aspirin failure, defined as occurrence of an acute coronary syndrome despite aspirin use, has been associated with a higher cardiovascular risk profile and worse prognosis. Whether this phenomenon is a manifestation of patient characteristics or failure of adequate platelet inhibition by aspirin has never been studied. We evaluated 174 consecutive patients with acute myocardial infarction. Of them, 118 (68%) were aspirin naive and 56 (32%) were regarded as having aspirin failure. Platelet ... [Abstract] [Full-text]

Articles on Aspirin published 21 January 2011:

Atherosclerosis and acetylsalicylic acid are independent risk factors for hemorrhage in patients with gastric or duodenal ulcer.   Anadolu Kardiyol Derg, 11(1): 53-6.

[Abstract] [Full-text]

Atherosclerosis and acetylsalicylic acid are independent risk factors for hemorrhage in patients with gastric or duodenal ulcer.   Anadolu Kardiyol Derg, 11(1): 53-6.

[Abstract] [Full-text]

Articles on Aspirin published 14 January 2011:

Multicenter randomized trial evaluating the efficacy of cilostazol on ischemic vascular complications after drug-eluting stent implantation for coronary heart disease: results of the CILON-T (influence of CILostazol-based triple antiplatelet therapy ON ischemic complication after drug-eluting stenT implantation) trial.   J Am Coll Cardiol, 57(3): 280-9.

[Abstract] [Full-text]

Articles on Aspirin published 4 January 2011:

A possible association of EMID2 polymorphisms with aspirin hypersensitivity in asthma.   Immunogenetics, 63(1): 13-21.

Aspirin-intolerant asthma (AIA) is an asthma phenotype characterized by the development of bronchoconstriction following ingestion of aspirin. Despite the well-defined pathological trigger, the underlying mechanisms of AIA are still unclear. With the biophysical characteristics of the human EMI domain-containing protein 2 (EMID2) gene in relation to the extracellular matrix deposition and epithelial-mesenchymal transition as pivotal characteristics of airway remodeling in asthma, we ... [Abstract] [Full-text]

Articles on Aspirin published 3 January 2011:

Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials.   Lancet, 377(9759): 31-41.

[Abstract] [Full-text]

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